This morning one of the gastroenterologists came and spoke about proton pump inhibitors (i.e. the class of drugs that are typically used to treat GERD like Prilosec and Nexium). A lot of the lecture went over my head, but here were two cool points that were mentioned:
-There can be a significant rebound when PPIs (proton pump inhibitors) are discontinued. Some practitioners argue that the withdrawal can actually create heartburn in patients who didn't have it.
-People taking PPIs are more likely to develop polyps in their stomach (specifically, gastric fundic gland polyps). This is kind of creepy, but apparently according to studies, these polyps don't seem to put people at risk for developing GI neoplasia. So far they appear to be silent.
|(Gastric fundic gland polyps - images courtesy of Medscape)|